Today, we have the ability to analyze large data bases, including patient registries, that reflect the broader range of patients more typically seen in clinical practice. To provide individualized care, clinicians need information that reflects their patient population. In the past, treatment trials have used small restrictive samples and relied on average treatment effects as their measure of success and produced conflicting results. These patients have persistent Lyme disease symptoms resulting from lack of treatment, under-treatment, or lack of response to their antibiotic treatment protocol. There is considerable uncertainty in the medical community regarding the best approach to treating patients with Lyme disease who do not respond fully to short-term antibiotic therapy. Lorraine Johnson, Mira Shapiro, Jennifer Mankoff - Open Access Healthcare 2018, 6(4), 124 ĪBSTRACT: Lyme disease is caused by the bacteria borrelia burgdorferi and is spread primarily through the bite of a tick.
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